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How nerve damage causes leg pain. Leg pain isn’t always just a muscle problem. When a nerve is irritated, compressed or damaged, it can send abnormal pain signals down the leg. Sciatica happens when the sciatic nerve is irritated, often around the lower back, causing pain that can travel from the lower back or buttock down the back of the leg and sometimes into the foot. You may also experience burning, tingling, numbness or weakness. Nerve problems can have different causes, including diabetes,
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