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Alaleuan osteonekroosi (ORN) on yleinen ja vakava pään ja kaulan syöpien sädehoidon komplikaatio, jonka ilmaantuvuus vaihtelee 4–30 prosentilla. ORN:n, erityisesti pitkälle edenneen ORN:n, hoito on ...

Six1 is a member of the six-homeodomain family of transcription factors. Six1 is expressed in multiple embryonic cell types and plays important roles in proliferation, differentiation and survival of ...

This past week was muscular dystrophy awareness week, which seems like a short amount of time to focus on such a heartbreaking disease. One in every 3500 boys in the US develops that debilitating and ...

South San Francisco, CA, Nov. 14, 2024 – The California Institute for Regenerative Medicine (CIRM), one of the world’s largest institutes dedicated to regenerative medicine, marked a historic ...

BACKGROUND: The regulation of gene expression is complex and occurs at many levels, including transcriptional and post-transcriptional, in metazoans. Transcriptional regulation is mainly determined by ...

年龄相关性黄斑变性（AMD）是老年人失明的主要原因。在地理性萎缩中，即常见且无法治疗的干性 AMD 的晚期，视网膜色素上皮 (RPE) 会出现细胞损伤和细胞死亡，RPE 是紧邻眼睛后部光敏感感光器 ...

基于干细胞的治疗策略能够治愈影响视网膜色素上皮 (RPE) 的疾病，而视网膜色素上皮 (RPE) 支持光感受器的存活和功能。本研究旨在评估将在超薄聚对二甲苯上单层培养的人胚胎干细胞衍生的 RPE ...

视网膜变性是一组致盲疾病，它们日益影响加州人的健康和福祉。据估计，到 2020 年，超过 450,000 万加州人将因年龄相关性黄斑变性 (AMD) 而遭受视力丧失或失明，AMD 是老年人视网膜变性疾病的 ...

研究目的 本研究计划的目的是开发一种主要的 AAV 候选药物，用于光遗传学视力恢复疗法，用于治疗因光感受器丧失而失明的患者。 影响 我们的光遗传学视力恢复 AAV 基因治疗候选药物将非侵入 ...

First year progress on grant ID1-06557, ” Generation and Characterization of High-Quality, Footprint-Free Human Induced Pluripotent Stem Cell (iPSC) Lines From 3000 Donors to Investigate Multigenic ...

Sponsorisé par le California Institute for Regenerative Medicine (CIRM) et hébergé par Cedars-Sinai, le 7e symposium annuel du réseau Alpha Clinics rassemble un large éventail de parties prenantes, ...