A Ukrainian drone attack at an industrial plant in central Russia has killed three people and injured 35 others, a Russian regional governor has said.

A Ukrainian pilot was killed and his F-16 fighter jet crashed as after Russia launched a huge aerial assault involving hundreds of drones and scores of missiles overnight, the Ukrainian military said on Sunday.

Russia launched its biggest aerial attack against Ukraine overnight, a Ukrainian official said Sunday, part of an escalating bombing campaign that has further dashed hopes for a breakthrough to end the three-year-old war.