Frizzled (FZD) proteins are the principal receptors of the Wnt signaling pathway. However, whether Wnt ligands induce FZD endocytosis and degradation remains elusive. The transmembrane E3 ubiquitin ...

Philip C. Almond does not work for, consult, own shares in or receive funding from any company or organization that would benefit from this article, and has disclosed no relevant affiliations beyond ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Dynamin 1 mediates fission of endocytic ...

Exactly three years ago today, Elon Musk tweeted that 90 percent of his tweet replies on what was then called Twitter were bot accounts. His insistence that Twitter was essentially one large bot farm ...

Over the past few years, AI has gone from limited chatbots to suddenly dominating the news cycle every single day. There are a range of AI chatbots you can access from ChatGPT to Gemini but one of the ...

Summary: Scientists have identified a natural compound combination that reverses aging-related brain cell decline and removes harmful Alzheimer’s-linked proteins. The treatment, combining nicotinamide ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Extracellular release and uptake of pathogenic ...

Only seven percent of American adults consume their daily recommended intake of fiber, according to the American Society for Nutrition. It’s a startling statistic and means the odds are high that ...

ABSTRACT: Amphiphilic triblock poloxamer 188 (P188) has demonstrated its therapeutic potential for muscle, cardiac and neurological injuries. While this surfactant is thought to primarily reseal the ...

What is fracking? You may have heard about the effects this oil and gas extraction technique have on the environment, but its impacts extend far beyond that. Between 2007 and 2016, oil production in ...

The original article, which was published in November 2019, was updated by Dr. Rick Mask in collaboration with Gina Neugebauer. Social capital is not a new term. In fact, it has been examined by many ...