Molecular structure reveals how HIV infects cells Date: September 12, 2013 ... Mar. 16, 2023 — The human immunodeficiency virus HIV-1 is able to infect various tissues in humans.

In the ongoing fight against HIV, scientists have taken a new step toward long-term control of the virus. Researchers have ...

Scientists have determined the structure of the protein package that delivers the genetic material of the human immunodeficiency virus (HIV) to human cells. A team of scientists at The Scripps ...

The crystallographic determination of the CCR5 receptor has been achieved, providing insights into its allosteric inhibition by Maraviroc, an HIV drug. The CCR5 receptor, which is known to act as ...

The researchers found that IP6 plays an important part in both the immature and mature phases of the HIV life cycle as the virus assembles its structure. “This small molecule acts in two different ...

This distinction is important because although inhibiting P-TEFb blocks replication of the HIV virus, P-TEFb is a vital protein in human cells and inhibiting it kills cells.

Once both molecules of the virus are bound to the cell membrane, the process of injecting viral RNA can begin. “Because HIV-1 is an integrating virus, blocking this process completely is essential to ...

A new paper published this week in the journal Nature describes how researchers pieced together the entire molecular structure of the protein shell of the HIV virus using GPU-based simulations.

Though treatments are available, there is no cure or vaccine from HIV, which impacts about 38 million people worldwide. It's difficult to target the RNA genome of the HIV virus in part because it ...

HIV is particularly tricky for the immune system to deal with. Not only does the virus infect and incapacitate some of the very immune cells that might otherwise defend against it, but it also ...