In this issue of The EMBO Journal, Chandler et al, demonstrate in a neonatal mouse model that maternal antibodies interfere ...

Several recent studies show that the E3 ligase RNF114 recognises a hybrid ADP-ribose-ubiquitin modification on substrate ...

Understanding temporal dynamics in tissue biology is key to linking transcriptomic snapshots to physiological function.

An epigenome-wide study uncovers ancestry-associated DNA methylation reprogramming in African prostate tumours, implicating enhancer dysregulation and developmental pathway activation in aggressive ...

Conjugation is mediated by a large molecular machinery termed Type IV secretion system (T4SS), embedded within the donor cell ...

Raw sequencing data are processed and aligned to give count matrices, which represent the start of the workflow. The count data undergo pre‐processing and downstream analysis. Subplots are generated ...

Peroxisomes are the cellular location of many antioxidants and are themselves significant producers of reactive oxygen species. In this report we demonstrate the induction of peroxisome biogenesis ...

The EMBO Journal has been EMBO's flagship publication for 40 years. With a scope that spans all areas of molecular biology, the journal has an international reputation for quality and originality. The ...

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Basic research, often termed fundamental, frontier, blue-sky, curiosity-driven—or even useless—is the pursuit of knowledge ...