Objective Long-term azithromycin treatment effectively prevents acute exacerbations of chronic obstructive pulmonary disease ...

Background and objectives IgG4-related disease (IgG4-RD) is a multi-system fibro-inflammatory disorder originally described in association with autoimmune pancreatitis (AIP), usually but not always in ...

Rationale Despite high prevalence of e-cigarette use (vaping), little is currently known regarding the health effects of secondhand nicotine vape exposure. Objective To investigate whether exposure to ...

Pulmonary rehabilitation has established itself as a vital and core therapy for people with chronic lung disease. Significant improvements are seen in several patient outcomes, for the thousands ...

Introduction We delivered a one-year weight management programme (Counterweight Plus, CWP) in participants with difficult-to-treat asthma and obesity in a single-centre randomised controlled trial ...

Introduction Despite improvements in pulmonary function, physical activity (PA) levels remain significantly lower than the general population, even at 1 year following lung transplantation (LTx).

Method Adults with a first-recorded code for breathlessness (index date) and subsequent coded diagnosis between 2007 and 2017 were included from a UK primary care database (CPRD-GOLD). Cox regression ...

Background Smoking has been considered an important risk factor for idiopathic pulmonary fibrosis (IPF) incidence. However, there are no population-based large-scale studies demonstrating the effects ...

Cigarette smoking is the leading cause of preventable death worldwide. It causes chronic lung disease and predisposes individuals to acute lung injury and pulmonary infection. Alveolar macrophages are ...

Background This study reports preliminary outcomes from a joint Respiratory Consultant and Speech and Language Therapist (SLT) ‘one stop’ cough clinic. Local and tertiary referrals were accepted.

Introduction Chronic rhinosinusitis with nasal polyposis (CRSwNP) affects a significant proportion of people with severe asthma (SA). Despite the effectiveness of anti-IL5/5R therapies in the ...

Introduction The benefits achieved during pulmonary rehabilitation (PR) are known to decline 6–12 months after the initial programme. There is no consensus on the best maintenance strategy.1 Previous ...