Targeting the WNT signaling pathway represents a promising strategy for cancer therapy. The field has evolved to include numerous inhibitors currently under preclinical and clinical investigation.

Researchers from the Leibniz Institute on Aging - Fritz Lipmann Institute (FLI) in Jena, Germany, the Molecular Biotechnology ...

A specific form of epigenetic aging, ACCA drift, accumulates in intestinal stem cells, silencing key genes through hypermethylation. Driven by age-related inflammation, weakened Wnt signaling and ...

The human gut renews itself faster than any other tissue: every few days, new cells are created from specialized stem cells.