Descovy belongs to a drug class called nucleoside reverse transcriptase inhibitors ... by blocking a certain enzyme that HIV needs to multiply. An enzyme is a type of protein.

ISL has considerable potency due to its high binding affinity for the reverse transcriptase enzyme and its ability to inhibit reverse transcription through multiple mechanisms, including ...

In order for HIV to replicate, it uses an enzyme called reverse transcriptase to translate its viral RNA into double-stranded DNA, which is then integrated into the nucleus of the host cell to ...

Unlike traditional antiretrovirals that target enzymes such as reverse transcriptase or protease, LEN binds directly to the capsid protein, disrupting several critical steps in the virus’s life cycle.

In this work, we investigate how proton transport and membrane potential regulate pH dynamics in an autocatalytic enzyme reaction within lipid vesicles ... lipase), predominantly performed in reverse ...

By testing a variety of substrates with XR and carbonic anhydrase (CA), we found that the reaction of the enzyme on the DNA scaffold can be accelerated or slowed down, depending on the substrate ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Stimulator of interferon genes (STING) is ...

Get detailed information on chikungunya, its clinical assessment and treatment. Reports of hospitalization for cardiac or neurologic events following vaccination with IXCHIQ in persons 65 years of age ...

High grade serous carcinoma (HGSC) is one of the most lethal ovarian cancers that is characterised by asymptomatic tumour growth, insufficient knowledge of malignant cell origin and sub-optimal ...