Several recent studies show that the E3 ligase RNF114 recognises a hybrid ADP-ribose-ubiquitin modification on substrate ...

Understanding temporal dynamics in tissue biology is key to linking transcriptomic snapshots to physiological function. Barkai et al. propose a turnover score derived from gene expression of shed ...

Conjugation is mediated by a large molecular machinery termed Type IV secretion system (T4SS), embedded within the donor cell ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. DNA i-motif structures are formed in the ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. Skeletal muscle regeneration involves a ...

Many compounds being considered as candidates for advanced biofuels are toxic to microorganisms. This introduces an undesirable trade‐off when engineering metabolic pathways for biofuel production ...

Peer ReviewDownload a summary of the editorial decision process including editorial decision letters, reviewer comments and author responses to feedback. This study identifies a pathway for oxidation ...

The compartmentalization of eukaryotic cells, which is essential for their viability and functions, is ensured by single or double bilayer membranes that separate the cell from the exterior and form ...

(A) The V2 vasopressin receptor (V2R) contains in its carboxyl‐terminal tail region clusters of Ser/Thr potential GRK phosphorylation sites (phosphocodes, green key). V2 activation stimulates Erk ...

Under normal conditions, SR proteins are hyperphosphorylated at their intrinsically disordered regions containing SR and SP dipeptides. Upon heat shock, SR proteins are rapidly dephosphorylated.

The photoreceptors required for post‐translational regulation of CO have been characterized. Mutations in the genes encoding the photoreceptors phytochrome A (phyA) and cryptochrome 2 (cry2) delay ...

Indeed, we demonstrate here that p19 inhibits RNA silencing in planta by sequestering siRNAs. In CymRSV‐infected plants, siRNAs are present in p19–siRNA complexes, while in plants infected with the ...