The 49ers are 12.5-point favorites, per the latest Titans vs. 49ers odds, and the over/under for total points scored is 44.5 a

The Tennessee Titans fell to 2-12 to the San Francisco 49ers (10-4) in Week 15 by a score of 37-24. The latest loss came one week after Tennessee won for only the second time this season on the road against the Cleveland Browns (3-11).

The Tennessee Titans face the Jacksonville Jaguars at Nissan Stadium on Nov. 30. Here are the scouting report and score prediction.

Jeffery Simmons will trust the authorities to find the perpetrators, as he and the Titans prepare for a Week 16 matchup against the severely shorthanded Kansas City Chiefs. The 28-year-old is in the midst of his best season yet, posting nine sacks, 32 solo tackles, 14 tackles for loss, two forced fumbles and 49 total pressures through 12 games.

The Browns started with a swing pass to RB Dylan Sampson, and as he tried to make a juke move, a Titans defender laid his shoulder into the ball to force a fumble that was returned to the Browns’ 8 yard line for a goal-to-go situation.

Kickoff from Huntington Bank Field is set for 1 p.m. ET. The Browns are 3.5-point favorites, according to the latest Titans vs. Browns odds. The over/under for total points scored is 33.5. Before making any Browns vs. Titans picks, make sure you check out the NFL picks from the SportsLine Projection Model.

The Tennessee Titans couldn't keep up with the methodical, forward-moving offense of the San Francisco 49ers, dropping the Titans in the loss column.

The San Francisco 49ers defense struggled some against the Tennessee Titans, but their offense had a huge day to mark the team’s fourth win in a row.