The Colts are currently riding a four-game losing streak, which is the fourth-longest active streak in the league. If the Colts want to end that, they'll have to dominate the 49ers in these three areas on Monday night.

San Francisco 49ers team reporter Briana Jeannel addresses fans’ biggest questions ahead of Week 16 vs. the Indianapolis Colts.

The Indianapolis Colts are on a four-game losing streak, and their playoff hopes are waning. However, there has been a bright spot for this team, and a bit of a surprising one at that -- the run defense.

The San Francisco 49ers cannot just walk into Indianapolis and beat the Colts without putting in a good effort; their roster is too strong for that. However, this is a team that is falling apart and they have a few glaring issues that can be exposed by the right team.

The Indianapolis Colts lost to the Seattle Seahawks 18-16 with 44-year old Philip Rivers starting at quarterback.

Since last playing, Philip Rivers has had another child — he has 10 now — and one of his daughters has given birth.