Israel’s sweeping attack across Iran struck at the heart of Tehran’s nuclear program, delivering a blow to the country’s ability to enrich uranium and potentially setting its nuclear ambitions back by months or years.

Smoke and flames filled the sky over Tehran as Israel struck oil and gas facilities in the Iranian capital and targeted more nuclear facilities during attacks that carried on into Sunday after starting two days earlier.

The Israeli military struck "over 170 targets" in Iran in three days, the Israel Defense Forces (IDF) said on Sunday.

Israel unleashed airstrikes across Iran for a third day and threatened even greater force as some Iranian missiles evaded Israeli air defenses to strike buildings in the heart of the country.

The Israeli military targeted Iranian nuclear facilities, research scientists and senior military commanders in dozens of preemptive airstrikes​.

A sixth round of nuclear talks between the United States and Iran, previously scheduled for Sunday, was canceled amid escalating tensions between Israel and Iran.

Trump proposed a U.S.-brokered trade deal as a path to peace between Israel and Iran, despite rising violence, a canceled round of nuclear talks, and no sign either side is willing to negotiate.

Iran launched multiple deadly waves of missiles and drones toward Israel into Saturday morning following Israel’s unprecedented strikes aimed at destroying Iran’s nuclear program and decapitating its military leadership.

The two sides were scheduled to meet for a sixth round of negotiations on Sunday. Oman, which was set to host the talks, said on Saturday that this round had been canceled.

Three people have been killed in Israel, according to officials and local media, with both sides saying the strikes will continue.