President Donald Trump on Sunday issued a stark warning to Iran against retaliating on U.S. targets in the Middle East while also predicting Israel and Iran would “soon” make a deal to end their escalating conflict.

Iranian news media and residents of Tehran say the damage from the latest Israeli strikes appears to be significant, with several apartment buildings badly damaged. Residents say they are hearing ambulance sirens and fire trucks racing to the scenes and rescue workers are working to find casualties in the rubble.

Residents of Tehran reported long lines at gas stations and traffic jams as people rushed to flee the city, anticipating more attacks from Israel. Officials told people near locations including refineries to leave if they could and recommended that people seek refuge in metro stations.

Iran's Supreme Leader Ali Khamenei reportedly seeks refuge in a Tehran bunker as Israel launched strikes. Following a Mashhad strike, sources indicate Israel spared Khamenei to give him a "final chance" to dismantle Iran's uranium enrichment program.