At least six people were killed and 24 others wounded early on Wednesday when Israeli strikes hit central Beirut and the city’s southern suburbs, the Lebanese health ministry said. A loud explosion

Hezbollah fired 200 missiles and drones into Israel in what Israeli media called an integrated attack with Iran, prompting fierce Israeli Defense Forces strikes.

The drone strike was the first within the city limits of Lebanon's capital since Israel-Hezbollah hostilities resumed last week.

It’s very challenging, it’s very uncertain, but we took a decision to keep our airspace open since day one of the war,” Lebanon's transport minister told NBC News.

With airstrikes rocking Beirut and Israeli troops advancing against Hezbollah, Lebanon’s government has broken a taboo by proposing the first direct talks with Israel in decades. But Lebanese officials say they want the fighting to end first — and it might be too late for that.

Israel struck central Beirut overnight and issued the first ever evacuation order for part of the capital, as Israel vows it will not stop until Hezbollah is defeated and nearly a million people are displaced in Lebanon alone.

Follow NBC News for live updates on the latest about the war with Iran, where the U.S. launched bunker buster bombs, while Israel struck Lebanon.

We speak with journalist Lylla Younes in Lebanon, where she says Israel’s “massacres are multiplying” amid the broader U.S.-Israeli war on Iran. Israeli strikes have killed nearly 700 people in Lebanon over the past two weeks,