Christina Applegate got vulnerable about the struggles she’s having as a result of multiple sclerosis. During a Tuesday broadcast of her podcast “MesSy,” which Applegate co-hosts with fellow actor Jamie-Lynn Sigler,

Christina Applegate is letting fans in on some of the details of her struggle against MS over the past three years.

Christina Applegate shared that she thinks her gastrointestinal symptoms are related to multiple sclerosis, explaining, "I get all the pain" from bowel movements.