Scientists discovered that hepatitis A viral replication requires specific interactions between the human protein ZCCHC14 and a group of enzymes called TENT4 poly(A) polymerases, and they used a ...

This story is part of a larger series on viroids and virusoids, small infectious RNAs. It is also the sixth installment in a series on hepatitis D virus, a virusoid-like pathogen that causes serious ...

HIV is infamous for its ability to hide in the human body for decades, typically requiring long-term treatment to prevent a ...

There are only three antivirals authorized by the US Food and Drug Administration (FDA) for treating COVID-19. If the ...

Researchers have found a way to block one strain of the influenza virus from accessing a human protein it needs to replicate in cells. The discovery could lead to highly effective ways to treat the ...

A new, nano-scale look at how the SARS-CoV-2 virus replicates in cells may offer greater precision in drug development, a Stanford University team reports in Nature Communications. Using advanced ...

A new combination of microscopy methods has revealed exquisite detail of the virus assembly process used by herpes simplex virus during replication. The research, published today in eLife, is ...

New antiviral drugs in development could offer the strongest line of defense yet against COVID-19 and other coronaviruses, ...

To better understand BKPyV replication and ways to prevent it, researchers in the UAB Department of Microbiology have published a single-cell analysis of BKPyV infection in primary kidney cells. Their ...

Viruses are finely tuned to their hosts, but mutations can and have produced strains that can jump from animals into humans. Sara Sawyer, a virologist at the BioFrontiers Institute of the University ...