Cytokines are a large group of bioactive small molecule proteins synthesized and secreted by immune and non-immune cells. There are various types of cytokines that belong to different families and ...

Scientists in the Blavatnik Institute at Harvard Medical School and MIT have created a new family of tools that, for the first time, illuminates the missing half of how the immune system uses ...

Structural equivalence is demonstrated through the comparison of a synthetic multinuclear metal complex (left) versus the designer enzyme in this report (right). A collaborative research team led by ...

Cytokines are secreted proteins critical for immune regulation, cell signaling, and tissue homeostasis. These cells are increasingly recognized as key tools in biomedical research, particularly in ...

Cytokines are small, secreted proteins that transmit messages between cells and members of this superfamily include chemokines, growth factors, interleukins, interferons, colony stimulating factors, ...

Exploring the strategy behind the introduction of receptor bias to reduce toxicity and improve efficacy; Key strategies for optimizing cytokine potency and mitigating their inherent toxicity while ...

Autoimmune diseases result from a complex interaction of immune system imbalances, marked by a breakdown in self-tolerance and sustained inflammation. At the core of this dysregulation are ...

A collaborative research team has successfully developed designer enzymes that exhibit both intrinsic and extrinsic functions by transplanting a synthetic trinuclear zinc center into a human cytokine.