Full-marker reagent portfolio supports mechanistic studies linking Hippo, TGF-β/BMP and WNT signalling cascades HUSTON, ...

The Smad2/3 pathway plays a key role in mediating TGF-β1 inhibition of branching morphogenesis and induction of connective tissue growth factor (CTGF) expression in embryonic lungs. Because a number ...

Transforming growth factor-beta (TGF-β), a well-known morphogen, is recognized for its role in regulating growth and development. The study is published in the journal Nature Communications. The ...

The liver's ability to communicate with other organs is crucial for maintaining homeostasis, particularly through signaling pathways. During liver regeneration, communication with organs such as the ...

Nuformix plc (LSE:NFX) has reported further preclinical findings for NXP002, its investigational inhaled treatment for idiopathic pulmonary fibrosis (IPF), progressive pulmonary fibrosis and related ...

Newswise — Researchers from the Cancer Science Institute of Singapore (CSI Singapore) at the National University of Singapore (NUS) have delineated novel molecular interactions affecting the activity ...

Nuformix plc reports statistically significant reductions in TGF-β/SMAD signalling following inhaled administration of NXP002 in a preclinical study, supporting its development as a potential ...

New research identifies the secreted protein SRPX2 as a molecular switch that stabilizes the TGF-beta receptor to drive ...

A new research paper was published in Genes & Cancer on February 5, 2023, entitled, "Mechanistically based blood proteomic markers in the TGF-β pathway stratify risk of hepatocellular cancer in ...

MicroRNA analysis of fine-needle aspirates from pancreatic cancer. Background: TGF-beta acts both as a tumor suppressor or tumor promoter depending upon cellular context and stage of tumor progression ...

In a finding that could reshape how scientists think about the hormones behind hair growth, researchers in China have shown that dihydrotestosterone (DHT), the androgen notorious for driving male ...