The ribosome serves as the essential molecular machine that translates genetic information carried by messenger RNA (mRNA) into functional proteins. Comprised of two distinct subunits, the ribosome ...

The discovery of ribosomes dates back to the 1950s, when George Palade first observed dense particles in the cytoplasm of cells using electron microscopy. These particles were later named "ribosomes" ...

Inside tiny cellular machines called ribosomes, chains of genetic material called messenger RNAs (mRNAs) are matched with the corresponding transfer RNAs (tRNAs) to create sequences of amino acids ...

A three-dimensional reconstruction of the eukaryotic 80S monosome from a frozen-hydrated electron microscopic preparation reveals the native structure of this macromolecular complex. The new structure ...

In the 1940s, scientists at the recently established National Cancer Institute were trying to breed mice that could inform our understanding of cancer, either because they predictably developed ...

LMU researchers uncover the mechanism by which ribosomes raise alarms in the cell. Ribosomes, the protein factories of the ...

Ribosomes, the protein factories of the cell, are essential for all living organisms. They bind to mRNA and move along the ...

In an effort to reveal the inner workings of a protein that serves as a cell's damage detection system, scientists at Johns ...

Polysome and ribosome preparations from normal rat liver and from a series of transplantable rat hepatomas of different growth rates were compared. All the hepatomas had a significantly higher ...

Angiogenin is a well-characterized enzyme that has a variety of important roles; it can trigger the growth of new blood vessels, is involved in cell survival, migration, and proliferation, and has ...

Scientists report a method for stable attachment of peptides to tRNAs, which has allowed them to gain new fundamental insights into ribosome function by determining the atomic-level structures of ...