Researchers revealed that abnormal delivery of zinc to lung cells contributes to obstructive pulmonary diseases. They further showed that mRNA splicing abnormalities are involved in the detailed ...

Philadelphia, April 30, 2025 – Researchers have developed a novel rat model that closely replicates the pathological features and physiological changes associated with human chronic obstructive ...

Charles Burger, MD: Pulmonary hypertension really refers to a state where the right heart is generating high pressures to circulate the blood through the lung. Pulmonary arterial hypertension is a ...

The severe acute respiratory syndrome (SARS) pandemic in Toronto resulted in a large number of autopsies on its victims. We describe the pulmonary pathology of patients who died in the 2003 Toronto ...

The current pathophysiology of COPD encompasses three main characteristics: emphysema, chronic bronchitis and small airway disease. Macrophages and neutrophils are implicated in this process; thus ...

Chronic obstructive pulmonary disease (COPD) is a major and increasing global health problem that results in progressive airway obstruction. Although effective bronchodilators have been developed, ...

Figure 1. Hyperinflation of the lungs points to a pulmonary cause of dyspnea. There are guidelines for the management of each as a separate condition, but how do you evaluate and treat them when they ...

"We found that metabolites associated with mucus hydration and adenosine metabolism were strongly associated with markers of COPD disease severity. These findings confirm previous studies implicating ...

Introduction Chronic obstructive pulmonary disease (COPD) is a common respiratory condition, affecting 4.5% of people over the age of 40 in the UK. The British Lung Foundation estimates 1.2 million ...

The diagnosis of COPD can be frustrating for both the patient and the physician, especially when a patient is identified as having the frequent-exacerbation phenotype. Counseling these patients is ...