Glioblastoma (GBM), the most malignant tumor of the central nervous system, is marked by its dynamic response to microenvironmental niches. In particular, this cellular plasticity contributes to the ...

Metabotropic glutamate receptors (mGluRs) are a family of G protein-coupled receptors that modulate excitatory neurotransmission and intracellular signalling pathways throughout the central nervous ...

Brief description: ELFN1 interacts with the apical surface of mGlu7 and acts as a positive allosteric modulator by triggering a conformational change of the receptor. This enabled development of an ...

Neurotransmitter receptors and ligands play a fundamental role in chemical signaling throughout the nervous system by controlling how messages are received and processed by neurons. Direct signaling ...

Deep inside the hippocampus, the brain's memory gateway, a team of neuroscientists has uncovered a form of synaptic rewiring ...

For many autistic people, a crowded cafe isn’t just noisy. Every clinking spoon sounds like a bell. Every flickering light feels like a strobe. Clinicians have diagnosed autism through behavioral ...