FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...

Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...

Lung cancer, notorious for its high mortality rates, is a leading cause of cancer-related deaths globally, with metastasis being the primary contributor to poor patient outcomes. A critical factor in ...

Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of ...

Senescence, aging, and age-related diseases represent complex biological phenomena with significant impacts on human health, and metabolism and metabolomics play pivotal roles in understanding their ...

Efficacy and safety of immune checkpoint inhibitors in Child-Pugh B and C hepatocellular carcinoma: Impact of treatment line, local therapy and bevacizumab combination. This is an ASCO Meeting ...

Plants rely on sugars not only as energy sources but also as regulators of cellular activities. Carbon starvation disrupts central metabolism, impairs growth, and forces cells to recycle stored ...

New funding led by Goldcrest Capital and Godfrey Capital to advance lead candidate JUN_01 for type 2 diabetes and obesity to first-in-human studies JUN_01 would be the first ever candidate to ...