Lentiviruses have the unique ability amongst retroviruses of being able to infect non-cycling cells. Vectors derived from lentiviruses have provided a huge advancement in technology and seemingly ...
Among these, lentivirus-based vectors, derived from the HIV-1 retrovirus, are of growing interest in gene and cell therapy, particularly in immuno-oncology, due to their ability to infect dividing ...
Figure 1: β-galactosidase expression in mouse liver following lentiviral transduction. We analysed liver toxicity in rodents by measuring the serum alanine aminotransferase (ALT) concentration ...
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