Israel's blistering attack with warplanes and drones against Iran’s nuclear and military structure has sparking an open conflict between the two long-time foes that threatens to escalate.

Israel and Iran traded deadly fire for a fourth day on Monday in their most intense confrontation in history, fuelling fears of a drawn-out conflict that could engulf the Middle East.

Iran fired a new wave of missile attacks on Israel early Monday, killing at least eight people, while Israel warned residents of part of Tehran to evacuate ahead of new strikes.

In a significant shift amid the ongoing and intensifying conflict, Iran is reportedly pleading for renewed negotiations after a series of devastating Israeli strikes severely impacted the nation’s military leadership and nuclear sites.

As the Iran-Israel conflict intensifies, the U.S. deploys the USS Nimitz aircraft carrier along with support tankers to bolster military readiness.

Dozens of others were injured overnight across Israel, the authorities said. Israel was striking military sites in Iran and the four-day-old conflict showed no sign of slowing.

CNN and Al Jazeera go all-in on Israel-Iran escalation, as international media coverage reflects deepening global divisions.

A Democratic senator introduced legislation to prevent President Donald Trump from using military force against Iran without Congress's authorization.