Solid tumors often provide a challenging environment for the T cells of our immune system. By reprogramming the metabolism of ...

Cancer cells survive therapy by dynamically rewiring their metabolism in response to nutrient availability, ...

Stimulating a key metabolic pathway in T cells can make them work more effectively against tumors when combined with immune checkpoint inhibitor therapy, according to a preclinical study. The findings ...

FAS, fatty acid synthase; FATP, fatty acid transporter protein; GPCR, G protein-coupled receptor; LPC, lysophosphatidylcholine; LXR, liver X receptor; PPARγ, peroxisome proliferator-activated receptor ...