The Buffalo Bills are favored by 10 points over the Cleveland Browns, but have been upset twice this season as big favorites.

Following their electric comeback Sunday to snap the New England Patriots’ 10-game win streak, the Buffalo Bills have won three straight and six of their last eight. The Bills trail the Patriots by one game in the AFC East,

Here are the full Week 16 AFC standings and who every team is facing: Record: 2-12. Next game: vs. Chiefs. Record: 2-12. Next game: vs. Texans. Record: 3-11. Next game: vs. Bills. Record: 3-11.

The Buffalo Bills vs. New England Patriots game kicks off at 1 p.m. ET/10 a.m. PT on Sunday, Dec. 14, 2025. The Week 15 game between the Buffalo Bills and New England Patriots will air on CBS, which means it'll also stream live on Paramount+. You can also tune in on mobile devices with NFL+.

But Allen and Buffalo were undeterred. Ray Davis had a huge kick return to open the second half, and Allen capped the drive with a 4-yard touchdown to Dawson Knox. Then, the maligned Buffalo defense, shredded throughout the first half, got a three-and-out, and the Bills marched down the field again, with Cook powering in from 3 yards out.

The Bills have another lengthy injury list, but there was also some good news as Dion Dawkins is back from an illness, and Christian Benford may play.

Kicker Matt Prater, defensive tackle Jordan Phillips, and offensive tackle Chase Lundt will all be inactive for the Bills this weekend.

Which of the teams in the AFC playoff picture pose the most problems for the Buffalo Bills in the 2026 postseason?

The Bills trailed last Sunday 21-0 to the Patriots before storming back for a 35-31 win. No team has more comebacks from a double-digit deficit this season than Buffalo who has done so three times. Sean McDermott’s crew is now within one game of first place New England.

As the season enters it's final few weeks, Sean McDermott issued an update on how the team is managing Dalton Kincaid's injury.