Researchers from Amsterdam UMC have overturned a key assumption in the biological pacemaker field. In a new preclinical study, they show that the transcription factor TBX18 does not generate true ...

GUADALAJARA, Mexico — "Somatic reprogramming is a strategy in which we are not modifying a single part of the cell, but we are reprogramming a normal cell to transform it into a pacemaker cell," said ...

With a new $3 million grant from the National Institutes of Health, Cedars-Sinai Heart Institute investigators are moving closer to their goal of developing a biological pacemaker that can treat ...

Using human embryonic stem cells to create a type of cardiac cells known as sinotrial (SA) node pacemaker cells, a team of scientists from Israel and Canada have developed a biological pacemaker that ...

Electrical pacemakers have become a backbone in therapeutic intervention for slow heart rhythms resulting from conduction system disease. Although decades of innovations have greatly improved the ...

WASHINGTON (AP) -- No batteries required: Scientists are creating a biological pacemaker by injecting a gene into the hearts of sick pigs that changed ordinary cardiac cells into a special kind that ...

Using gene therapy, researchers have managed to temporarily restore a normal heart rate in pigs with abnormal heart rhythms by reprogramming cardiac muscle cells to act as “biological pacemakers.” The ...

For more than a decade, TBX18 has been reported to reprogram working ventricular cardiomyocytes into sinoatrial‑node–like pacemaker cells, based on widely cited high‑impact papers. Using low ...