Ion channels are narrow passageways that play a pivotal role in many biological processes. To model how ions move through ...

Scientists have taken a major step toward mimicking nature’s tiniest gateways by creating ultra-small pores that rival the dimensions of biological ion channels—just a few atoms wide. The breakthrough ...

Respiratory supercomplex formation relieves molecular strain of mitochondrial membranes and reshapes global protein motions, linking membrane reorganization to respiratory function.

In every living cell, there are membranes—and in every membrane there are proteins, each of which acts as a chemical gatekeeper. Rather than passively letting ions pass in and out of the cell, these ...

A revolution has occurred in the field of pharmaceutical development due to the development of drugs that target membrane proteins. It is estimated that one-third of currently available drugs target G ...

Living organisms share an ancestor called the last universal common ancestor, or LUCA. LUCA is estimated to have lived ...

Researchers shrink solid-state nanopores to sub-nm size via voltage-driven precipitation/dissolution, creating tunable pores that mimic ion channels for studying confined ion transport.

Researchers led by UChicago Pritzker School of Molecular Engineering’s Chong Liu and Northwestern’s George Schatz have developed a tunable system that selectively controls chemical transport at the ...