A pathogen's ability to infect or damage its host tissues is determined by the virulence factors. These are often molecules synthesized by bacteria or viruses and encoded in their genome, but they may ...

Various microbes harness the actin polymerization machinery through their surface proteins to allow intracellular motility within host cells, but other virulence factors regulate dissemination. The ...

Despite significant medical advances over the past 25 years, infectious diseases remain a major global health challenge, ...

This is a preview. Log in through your library . Abstract Numerous bacteria secrete low molecular weight compounds termed siderophores that have a high affinity for iron ions. Siderophores have a well ...

New research suggests that reducing virulence in drug resistant infections rather than trying to kill bacteria outright may offer an alternative approach to treatment. The study revealed how two ...

Using a chemical genetics approach, researchers identified the compound M21, which inhibits the expression of multiple virulence factors in Staphylococcus aureus via inhibition of the bacterial enzyme ...

In a recent study published in the journal Nature Communications, researchers report that the heterogeneity of Group A streptococcal infections and the transition of local to systemic infections ...

A research team has developed a novel chemical tool to reveal how bacteria adapt to the host environment and control host cells. This tool can be used to investigate bacterial interactions with the ...

What Is Quorum Sensing? Individual bacteria use quorum sensing to detect and respond to changes in cell density as a coordinated group. For example, the first reported evidence of quorum sensing was ...