Peter Searson is leading a Johns Hopkins University team that is unravelling how Alzheimer's and other diseases disrupt the blood-brain barrier, the complex interface that allows or blocks the passage ...

Repeated head knocks cause long-term damage to the delicate blood-brain barrier, potentially driving chronic traumatic encephalopathy (CTE), a neurodegenerative condition that affects some former ...

Blood-brain barrier drug delivery reached a landmark: the FDA’s March 2026 accelerated approval of Denali Therapeutics’ ...

Scientists from the University of Liverpool and their global collaborators have highlighted the most effective treatments for neurological diseases by overcoming one of medicine's most difficult ...

The blood-brain barrier weakens during normal aging and in neurodegenerative disease, but the reasons are not fully understood. In the February 26 Nature, scientists led by Tony Wyss-Coray and Carolyn ...

“Glioblastoma multiforme (GBM) remains a lethal brain tumor characterized by poor response to chemotherapy and limited blood–brain barrier (BBB) permeability” The study was led by first and ...

Scientists have developed a lipid nanoparticle system capable of delivering messenger RNA (mRNA) to the brain via intravenous injection, a challenge that has long been limited by the protective nature ...