By focusing on chromatin-modifying enzymes, viral proteins, and noncoding RNAs, the researchers hope to uncover new pathways for a functional cure for chronic hepatitis B. The review highlights the ...

Hepatitis B virus (HBV) is a significant public health problem, with over 296 million people chronically infected worldwide. Despite the availability of a safe and effective vaccine for over 40 years, ...

Chronic hepatitis B (CHB) is a long-term infection of the liver caused by the hepatitis B virus (HBV). While acute hepatitis B infection is often resolved by the immune system, CHB occurs when the ...

Drug combination reaches key threshold for 'functional cure' of chronic liver infection that affects more than 250 million people worldwide An international team of researchers led by Chinese medical ...

Arbutus Biopharma had made no secret of its plans to step up its work on imdusiran. Now, the company has regained the China rights to the potential functional cure for hepatitis B. China-based Qilu ...

Hepatitis B virus infection remains one of the leading causes of liver disease, including cirrhosis and hepatocellular carcinoma. Despite widespread vaccination and antiviral treatments, millions of ...

Liver specialist Maurizio Bonacini is in the race for a cure for hepatitis B, one of the world’s most widespread diseases and a top cause of liver cancer around the globe. “It’s the last frontier,” ...

– Oral presentation highlights significant reduction in HBV DNA integration and other clinically-relevant biomarkers from the EBT-107 therapeutic candidate in preclinical mouse models WATERTOWN, Mass.