In patients with AAV, 2 of the novel inflammatory biomarkers evaluated—the Systemic Immune-Inflammatory Index and the Systemic Inflammatory Response Index—recovered after AAV disease-inducing ...

This novel approach integrates diverse types of information by combining clinical parameters with imaging techniques like CT scans or laboratory data.

Future research should focus on illuminating how different interstitial lung disease subtypes affect outcomes in AAV. Interstitial lung disease (ILD) patterns differ between patients with ...

CNS-directed AAV gene therapy shows milder immune responses compared to systemic administration, reducing peripheral immune activation and systemic toxicities. Direct CNS delivery can bypass ...

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